Side N
Dorado v4 to v6 — What Changed, How Much, and Whether It Was Good
Which sources back which section of this article, and what its evidence base looks like.
Which sources back which section
| Section | Sources behind it |
|---|---|
| What Changed | Wick, “ONT-only accuracy: 5 kHz and Dorado” (2023); Wick, “Yet another ONT accuracy test: Dorado v0.5.0” (2023); Wick, “Dorado v1.0.0 and the v5.2.0 basecalling models” (2025); Wick, “Dorado v2.0.0: no more sup?” (2026); Wick, “Dorado v2.0.0 part 2: assembly polishing” (2026); Wick, “Dorado v2.0.0 part 3: methylation” (2026); Oxford Nanopore, Dorado release notes; Oxford Nanopore, Dorado model list; Oxford Nanopore, London Calling 2024 news release; Oxford Nanopore, accuracy page; Oxford Nanopore, London Calling 2026 technology talk; Dorado GitHub issue #1565 (2026); Prior et al., J Clin Microbiol (2025); Biggel et al., bioRxiv preprint (2026) |
| In What Order | Wick, “ONT-only accuracy: 5 kHz and Dorado” (2023); Wick, “Yet another ONT accuracy test: Dorado v0.5.0” (2023); Wick, “Dorado v1.0.0 and the v5.2.0 basecalling models” (2025); Wick, “Dorado v2.0.0: no more sup?” (2026); Wick, “Dorado v2.0.0 part 2: assembly polishing” (2026); Wick, “Dorado v2.0.0 part 3: methylation” (2026); Oxford Nanopore, Dorado release notes; Oxford Nanopore, London Calling 2024 news release; Oxford Nanopore, accuracy page; Oxford Nanopore, blog on transformer basecalling (2026); Oxford Nanopore, London Calling 2026 technology talk; Dorado GitHub issue #1565 (2026); Prior et al., J Clin Microbiol (2025); Biggel et al., bioRxiv preprint (2026); Kulkarni et al., Nat Commun (2026) |
| The Argument | Wick, “Dorado v1.0.0 and the v5.2.0 basecalling models” (2025); Wick, “Dorado v2.0.0: no more sup?” (2026); Wick, “Dorado v2.0.0 part 2: assembly polishing” (2026); Wick, “Dorado v2.0.0 part 3: methylation” (2026); Oxford Nanopore, Dorado release notes; Oxford Nanopore, blog on transformer basecalling (2026); Oxford Nanopore, London Calling 2026 technology talk |
| What Others Add | Wick, “Yet another ONT accuracy test: Dorado v0.5.0” (2023); Wick, “Dorado v1.0.0 and the v5.2.0 basecalling models” (2025); Wick, “Dorado v2.0.0: no more sup?” (2026); Oxford Nanopore, accuracy page; Oxford Nanopore, blog on transformer basecalling (2026); Dorado GitHub issue #1565 (2026); Prior et al., J Clin Microbiol (2025); Biggel et al., bioRxiv preprint (2026); Kulkarni et al., Nat Commun (2026) |
| Was It Good | Wick, “Dorado v1.0.0 and the v5.2.0 basecalling models” (2025); Wick, “Dorado v2.0.0: no more sup?” (2026); Wick, “Dorado v2.0.0 part 2: assembly polishing” (2026); Wick, “Dorado v2.0.0 part 3: methylation” (2026); Oxford Nanopore, Dorado release notes; Oxford Nanopore, Dorado model list; Oxford Nanopore, Dorado documentation on models; Proffitt, Bio-IT World (2024); Oxford Nanopore, blog on transformer basecalling (2026); Oxford Nanopore, London Calling 2026 technology talk; Dorado GitHub issue #1565 (2026); Prior et al., J Clin Microbiol (2025); Biggel et al., bioRxiv preprint (2026); Kulkarni et al., Nat Commun (2026) |
What the evidence base looks like
- 18Sources behind this article
- 18Read in full
- 9Independent studies and tests
- 7From the vendor itself
| What the source is | How many | How they were read |
|---|---|---|
| Independent measurement — a researcher’s published test series, two peer-reviewed papers and a preprint | 9 | All in full |
| The vendor’s own record — release notes, documentation, news, a blog post and a conference talk | 7 | All in full; the talk through its published captions |
| A user report on the public issue tracker, with the vendor’s replies | 1 | In full, with every reply |
| Independent reporting | 1 | In full |
Reliable
Reliable, but with an interestWorth believing and reliableWeak on both, and used with careHonest, but thin
Worth believing